1、【单选题】which one of the following about translation is true ( ) a、from3′ end to 5′ end of mrna b、directed by 28srrna c、polypeptide growth is from n to c terminus d、polypeptide growth is from c to n terminus e、directed by 16srrna
2、【单选题】which one is initiation codon and also encodes for met a、cuu b、acg c、cag d、aug e、ucg
3、【单选题】the stop codons are ( ) a、aaa ccc ggg b、uaa uag uga c、uca aug agu d、uuu uuc uug e、cca ccg ccu
4、【单选题】how many codons encode for the 20 amino acids（ ） a、16 b、20 c、61 d、64
5、【单选题】besides met, which amino acid has only one codon ( ) a、trp b、pro c、val d、arg e、his
6、【单选题】deletion or insertion in mrna may alter the primary structure of proteins, which is mostly related to ( ) of genetic codons. a、universal b、wobble c、degeneracy d、commaless e、conservative
7、【单选题】the first base of anticodon loop on trna is i (inosine), which can not pair to ( ) a、u b、a c、c d、g
8、【单选题】which rrna is not included in eukaryote ribosome ( ) a、28s b、5.8s c、18s d、5s e、16s
9、【单选题】the initiation factor that dissociates the two subunits of prokaryotic ribosome is ( ) a、rf-l b、eif-1 c、if-2 d、ef-tu e、if3
10、【单选题】the inhibitive mechanism of interferon to virus is to inactivate eif2 by( ) a、phosphorylation b、caboxylation c、adp- d、methylation e、acetylation
17.4mini-test
1、【单选题】about sirna, which is false ( ) a、endogenous or exogenous dsrna b、degrade mrna c、single strand d、completely paired to target mrna
2、【单选题】histone modification does not include( ) a、phosphorylation b、acetylation c、methylation d、ubiquitylation
3、【单选题】the sigma factor(σ) that controls housekeeping gene transcription is ( ) a、σ70 b、σ32 c、σ38 d、σ54
4、【单选题】the following description about housekeeping genes, which one is false( ) a、their expression are constitutive b、their expression are less affected by environmental factors c、their products are absolutely necessary to living cells d、their expression are inducible
5、【单选题】ldh expression is tissue-specific, which type is relatively high expressed in liver? a、ldh1 b、ldh2 c、ldh3 d、ldh4 e、ldh5
6、【单选题】trp operon using transcription ( ) to inhibit gene expression a、activation b、attenuation c、repression d、inhibition
7、【单选题】catabolite gene activation protein (cap) regulate positively on transcription of lac operon genes, it can be activated by ( ) a、camp b、cgmp c、glucose d、gtp
8、【单选题】the repressor protein bind with ( ) on lac operon a、p b、o c、cap d、z
9、【单选题】the inducer of lac operon is a、lactose b、glucose c、arabinose d、galactose
10、【多选题】the cis-acting elements in eukaryotes includes ( ) a、gc box b、caat box c、tata box d、enhancer e、silencer
11、【多选题】the eukaryotic gene expression can be regulated at( ) a、chromatin activation b、transcription c、mrna processing d、translation initiation e、post-translational processing
12、【多选题】the motifs in regulatory proteins that accout for dna-protein interaction include ( ) a、helix-turn-helix b、zinc finger c、leucine zipper d、strand turn strand
13、【简答题】what are the expression regulations at transcription level?
14、【简答题】please describe the biological significance of gene expression regulation